Fe3+-Montmorillonite K10 as an Efficient, Green and Reusable Heterogeneous Catalyst for Synthesis of Mannich Type Reaction under Solvent-free Condition

A simple and efficient one-pot three-component synthesis of Mannich type reaction has been developed using recyclable Fe+3-montmorillonite K10 (Fe+3@K10) under solvent-free condition. The reaction of aromatic aldehydes, aromatic anilines and aryl ketones produced β-amino carbonyl derivatives in good to excellent yields. The developed method making use of a recyclable catalyst is economical and eco-friendly and affords good yields under mild reaction conditions.